Dilated Juxtacortical Perivascular Spaces and Venous Cerebral Microbleeds in Cerebral Amyloid Angiopathy‐Related Inflammation

C erebral amyloid angiopathy-related inflammation (CAA-ri) is a rare subtype of CAA.It is characterized by amyloid β (Aβ) depositions within walls of leptomeningeal and cortical vessels, combined with perivascular, transmural, or intramural inflammation. 1CAA-ri showed greater disease severity than noninflammatory CAA during acute and subacute phases. 2 Therefore, early recognition and initiation of immunosuppressive treatment could improve the disease prognosis. 1Herein, we report a patient diagnosed with probable CAA-ri, emphasizing the imaging features presented with 5T magnetic resonance imaging (MRI).A 64-year-old woman developed chronic cognitive decline and headache, with subacute headache aggravation for 1 month.In 2017, she started with memory impairment of recent events and reduced social activities, which slowly progressed.She presented with a moderate episodic headache in March 2021.In May 2022, the headache became more severe and frequent, and the patient needed to stay in bed.She was admitted to our hospital in June 2022.On cognitive evaluation, her Mini-Mental State Examination (MMSE) score was 21, and her Montreal Cognitive Assessment (MoCA) score was 11.Other neurological examinations did not show evident abnormities.The apolipoprotein E gene test revealed ε4/ε4 homozygosity.Cerebrospinal fluid examination displayed normal open pressure, cell count, protein level, and glucose level.