衰老
细胞衰老
癌症
癌症研究
医学
生物
内科学
遗传学
基因
表型
作者
Eric Gilson,Pierre Soubeyran,Éric Solary
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2024-04-04
卷期号:14 (4): 635-638
标识
DOI:10.1158/2159-8290.cd-24-0089
摘要
Summary: Cellular senescence has paradoxical effects on cancer emergence, progression, and therapeutic response. We herein identify four lessons that emerged from studying senescence interaction with cancer and emphasize four bottlenecks in the therapeutic manipulation of cellular senescence to prevent or cure cancer.
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