Decreased Work Capability Related to High-Altitude Exposure

The unique environment of high altitude can affect the work capacity of those not accustomed to it, and in some cases, it can even endanger their lives. Studying the effect of high-altitude exposure on work capacity is important. Still, there are few reviews on this topic. We aimed to summarize the parameters used to evaluate work capability in a high-altitude environment, the potential pathophysiological mechanisms, and the available pharmacological and non-pharmacological strategies for improvement.