Immunochromatographic Diagnosis In this article number 2502574, Shuai Zheng, Bing Gu, Chongwen Wang, and co-workers propose a universal colorimetric ICA platform that integrates broad-spectrum recognition by 4-mercaptophenylboronic acid with dual signal enhancement–both colorimetric and catalytic–mediated by a biomimetic magnetic nanozyme. This platform, for the first time, enables simple, convenient, ultrasensitive, and simultaneous screening of multiple respiratory bacteria and virus.