肉芽肿伴多发性血管炎
苯拉唑马布
嗜酸性
医学
免疫学
发病机制
嗜酸性粒细胞
显微镜下多血管炎
炎症
疾病
皮肤病科
美波利祖马布
血管炎
病理
哮喘
作者
Federico Spataro,Antonio Giovanni Solimando,Attilio Di Girolamo,Angelo Vacca,Roberto Ria
摘要
Eosinophilic granulomatous polyangiitis (EGPA) is a rare autoimmune disease characterized by multisystemic inflammation, with eosinophils playing a central role in its pathogenesis. Traditional management relies heavily on corticosteroids and immunosuppressants, which are associated with significant side effects. The emergence of biologic agents, such as benralizumab, offers targeted therapeutic options by inhibiting the interleukin-5 receptor α, thereby reducing eosinophilic inflammation.
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