生物相容性
材料科学
复合数
3D打印
人骨
复合材料
生物医学工程
3d打印
抗压强度
骨组织
机械强度
纳米技术
人类血液
人造骨
生物材料
三维打印
生物相容性材料
作者
Hao Wang,S Wang,Jinzhi Ren,Shengli Zhu,Qianying Guo,Tadashi Fujieda,Akihiko Chiba
标识
DOI:10.1021/acsbiomaterials.6c00501
摘要
Traditional biomedical metallic materials, such as Ti, Ti alloys, and CoCrMo alloy, have high density and relatively limited biocompatibility, which would affect human bone repair. In this work, the CoCrMo/hydroxyapatite (HA) composite for biomedical applications is synthesized by the three-dimensional (3D) printing technology. The biocompatibility, blood compatibility, and mechanical properties are investigated in detail. The composite with 50 vol % HA exhibits good biocompatibility and blood compatibility, superior to commonly used medical materials. And this advantage tends to be more obvious with the extension of the duration. Meanwhile, the CoCrMo/HA composite can maintain a compressive strength of 724.4 MPa, which meets the requirement of human bone repair. This work provides a reference for the preparation of biomedical composites, and the as-formed composites may become a new choice for bone repair.
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