生物相容性材料
纳米技术
材料科学
组织工程
多孔性
工程类
生物医学工程
复合材料
作者
Fouad Junior Maksoud,Fer Velazquez de la Paz,Alice Hann,Jeerawan Thanarak,Gwendolen C. Reilly,Frederik Claeyssens,Nicola Green,Yu Shrike Zhang
摘要
The field of biomaterials has grown rapidly over the past decades. Within this field, porous biomaterials have played a remarkable role in: (i) enabling the manufacture of complex three-dimensional structures; (ii) recreating mechanical properties close to those of the host tissues; (iii) facilitating interconnected structures for the transport of macromolecules and cells; and (iv) behaving as biocompatible inserts, tailored to either interact or not with the host body. This review outlines a brief history of the development of biomaterials, before discussing current materials proposed for use as porous biomaterials and exploring the state-of-the-art in their manufacture. The wide clinical applications of these materials are extensively discussed, drawing on specific examples of how the porous features of such biomaterials impact their behaviours, as well as the advantages and challenges faced, for each class of the materials.
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