细胞
药品
癌症
药物开发
癌细胞
抗癌药物
计算生物学
癌症研究
生物
药理学
生物化学
遗传学
作者
Jacob B. Geri,William Pao
出处
期刊:Cancer Discovery
[American Association for Cancer Research]
日期:2024-04-04
卷期号:14 (4): 639-642
标识
DOI:10.1158/2159-8290.cd-24-0088
摘要
Cell surface proteins represent ideal therapeutic targets because of their accessibility to antibodies, T cell-directed therapies, and radiotherapies, but there are only 25 therapeutically relevant cell surface targets for which cancer therapies are approved in the United States or European Union. This commentary calls for intensified research into mapping the universe of cell surface proteins - the cell surfaceome - in order to accelerate cancer drug development.
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