Nickel/Photoredox‐Catalyzed Reductive Aldol Reaction

A dual nickel/photoredox‐catalyzed reductive aldol reaction using readily available alkyl bromide and α‐silylamine as bench‐stable hydride source and organic reductant is reported. A variety of β‐hydroxyl carbonyl compounds can be efficiently synthesized under mild conditions. The reaction exhibits broad substrate scope, accommodating various (hetero)aromatic and aliphatic aldehydes, as well as acyclic and cyclic α,β‐unsaturated carbonyls.