Copper‐Catalyzed Three‐Component Silylamidation of Terminal Alkynes

Herein, the successful development of a copper‐catalyzed three‐component silylamidation of alkynes, involving hydrosilanes and picolinamides, is described. This methodology provides an innovative and efficient route for the production of diverse silylated enamides, distinguished by its broad substrate compatibility and exceptional functional group tolerance. The synthetic versatility of this reaction is exemplified by its application in the late‐stage modification of substrates featuring complex motifs. Moreover, detailed studies on the reaction mechanism have been conducted through various mechanistic experiments.