The effects of administration of theLactobacillus gasseristrain CP2305 on quality of life, clinical symptoms and changes in gene expression in patients with irritable bowel syndrome

Although probiotics have been proposed to benefit IBS patients, objective clinical evidence and elucidation of the functional mechanism remain insufficient. Our study demonstrated that CP2305 administration beneficially influences IBS patients in both subjective and objective evaluations, and gene expression profiling provided insights into the functional mechanism.