Successful Pregnancies after Human Renal Transplantation

IN May, 1956, one of a pair of twenty-one-year-old identical twin females from Oklahoma was being studied as a potential recipient for a kidney transplant from her twin sister. Both were childless, having been married for less than a year. The ailing twin, with a three-year history of chronic glomerulonephritis, was in a dire preterminal state, with hypertension (blood pressure of 190 systolic, 120 diastolic), congestive heart failure only partially helped by digoxin and severe oral and gastrointestinal hemorrhage. Extra-corporeal hemodialyses were required on three occasions to sustain life until the necessary preliminary studies were completed.At that time there . . .