Determination and extraction of glycyrrhizic acid in licorice

Extraction,purification and determination methods of glycyrrhizic acid in Licorice were surveyed in this paper.The extracting efficiency of dilute ethanol solvent for glycyrrhizic acid was higher than water extraction,and ammonia appended to ethanol solution can increase the effect of extraction.Ultrasound method,microwave-assisted method and supercritical CO2 fluid extraction were more effective than the conventional techniques,due to the short extraction time,low consumption of solution and energy.The modern analytical methods such as TLC、HPLC and CE can determine the content of glycyrrhizic acid rapidly and exactly.