Palladium-Catalyzed Reductive Heck Coupling of Alkenes

DOI of original article: https://doi.org/10.1016/j.trechm.2019.05.007 (Trends in Chemistry 1, 572–587; 2019) A mistake was present in the published version of the review article ‘Palladium-Catalyzed Reductive Heck Coupling of Alkenes’ by Oxtoby et al. The manuscript erroneously did not include an Acknowledgements section. An Acknowledgements section has now been provided. Financial support for this work was provided by the National Institutes of Health (5R35GM125052-02), the National Science Foundation (Graduate Research Fellowships to L.J.O. and J.A.G.: NSF/DGE-184247, NSF/DGE-1346837), and Bristol-Myers Squibb. Palladium-Catalyzed Reductive Heck Coupling of AlkenesOxtoby et al.Trends in ChemistryJune 20, 2019In BriefThe Mizoroki–Heck reaction is one of the most-studied palladium-catalyzed cross-coupling reactions, representing a powerful method of forming C–C bonds between diverse substrates with broad functional group compatibility. However, the reductive variant has received considerably less attention. In this review, we summarize distinct mechanistic aspects of the reductive Heck reaction, highlight recent contributions to the field, and discuss potential applications of the reductive Heck reaction in the pharmaceutical industry. Full-Text PDF