芳基
催化作用
化学
胺气处理
小学(天文学)
光化学
催化循环
组合化学
基础(拓扑)
光催化
有机化学
烷基
数学分析
物理
数学
天文
作者
Geyang Song,Qi Li,Ding-Zhan Nong,Jiuzhou Song,Gang Li,Chao Wang,Jianliang Xiao,Dong Qian Xue
标识
DOI:10.1002/chem.202300458
摘要
This paper reports a photochemical C-N coupling of abundant, but less reactive aryl chlorides, with structurally diverse primary and secondary amides by Ni-mediated without an external photocatalyst. Under the irradiation of light (390-395 nm) with a soluble organic amine as the base, the reaction allows for the successful transformation of (hetero)aryl chlorides to a wide range of N-aryl amides. More than 60 examples are shown, demonstrating the feasibility and applicability of this protocol in organic synthesis. Mechanic studies indicate that this amidation proceeds via a Ni(I)-Ni(III) catalytic cycle.
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