医学
苦恼
癌症
老年学
环境卫生
内科学
临床心理学
作者
David Shu Cheong Hui,Vickie E. Baracos,Naoharu Mori,Satomi Okamura,Tomomi Yamada,Tomofumi Miura,Ryohei Tatara,Takaomi Kessoku,Yoshinobu Matsuda,Keita Tagami,Hiroyuki Otani,Masanori Mori,Tomohiko Taniyama,Nobuhisa Nakajima,Erika Nakanishi,Jun Kako,Tatsuya Morita,Mitsunori Miyashita
标识
DOI:10.1016/j.clnesp.2024.02.027
摘要
Abstract
Background & Aims
There is no definition of nutrition impact symptoms (NISs) in cancer care. Moreover, there is a lack of evidence on the associations of NISs with dietary intake and eating-related distress (ERD) in advanced cancer. Therefore, this study aimed to determine the associations of NISs with dietary intake and ERD in patients with advanced cancer. Methods
This study entailed a secondary analysis of a multicenter self-reported questionnaire designed to develop measurements that assess ERD experienced by patients. Participants evaluated their dietary intake and 19 symptoms regarded as NISs using a 10-point scale. To determine the association between dietary intake and the number of NISs with a score ≥4, estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the logistic regression model were calculated. Furthermore, to assess the association between ERD and the number of NISs with a score ≥4, multiple regression analysis was performed. Results
A total of 302 patients were included in the analysis. The higher the number of NISs with a score ≥4, the lower the dietary intake tended to be. In the logistic regression model, significantly higher adjusted ORs than in the no NISs with a score ≥4 group were observed in the 4–6 NISs group, 7–9 NISs group, and 10 or more group (0.19 [95% CI, 0.07–0.52], p=0.001; 0.11 [95% CI, 0.03–0.42], p=0.001; 0.07 [95% CI, 0.01–0.36], p=0.002, respectively). In the multiple regression analysis, the number of NISs with a score ≥4 was identified as one of the factors significantly associated with ERD. Conclusions
Having 4 or more NISs with a score ≥4 was shown to be predictive of the likelihood of reduced dietary intake. Furthermore, the higher the number of NISs with a score ≥4, the more likely the eating-related quality of life was impaired in advanced cancer.
科研通智能强力驱动
Strongly Powered by AbleSci AI