视神经脊髓炎
低钠血症
医学
光谱紊乱
复视
儿科
多发性硬化
磁共振成像
介绍(产科)
内科学
外科
免疫学
放射科
精神科
作者
Huaxing Meng,Jing Wang,Jiaqi Hou,Rui‐Qin Liu,Meini Zhang
标识
DOI:10.1080/00207454.2023.2277666
摘要
Neuromyelitis optica spectrum disorders (NMOSD) is often misdiagnosed or delayed because of the complex and diverse clinical manifestations, especially the atypical initial presentation. Hyponatremia can be an infrequently isolated initial presentation of NMOSD and is associated with hypothalamus involvement. Awareness of this mechanism will help clinicians to identify NMOSD early, treat it in time and improve the prognosis.We describe a 36-year-old woman who developed repeated hyponatremia and then experienced diplopia. Serum AQP4, MOG, MBP and GFAP antibody were detected, and NMOSD was finally diagnosed.She responded well to high-dose glucocorticoids. Sequential treatment with mycophenolate mofetil (MMF) was prescribed. Two-month follow-up revealed full recovery. So far, after 10 months, the patient still has no recurrence.For young patients, repeated hyponatremia, with or without slight fever, and no evidence of obvious infection, brain magnetic resonance imaging (MRI) and serum AQP4/MOG antibody detection may be useful to determine whether there is a possibility of NMOSD.
科研通智能强力驱动
Strongly Powered by AbleSci AI