液体活检
胎儿游离DNA
活检
医学
皮肤活检
病理
生物标志物
内科学
生物
癌症
怀孕
胎儿
生物化学
产前诊断
遗传学
作者
Jingwen Ma,Yan Teng,Yue Huang,Xiaohua Tao,Yu Fan
出处
期刊:Methods in molecular biology
日期:2023-01-01
卷期号:: 247-262
标识
DOI:10.1007/978-1-0716-3346-5_17
摘要
Liquid biopsy, also known as fluid biopsy or fluid-phase biopsy, is the sampling and analysis of the blood, cerebrospinal fluid, saliva, pleural fluid, ascites, and urine. Compared with tissue biopsy, liquid biopsy technology has the advantages of being noninvasive, having strong repeatability, enabling early diagnosis, dynamic monitoring, and overcoming tumor heterogeneity. However, interest in cfDNA and skin diseases has not expanded until recently. In this review, we present an overview of the literature related to the basic biology of cfDNA in the field of dermatology as a biomarker for early diagnosis, monitoring disease activity, predicting progression, and treatment response.
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