泛素连接酶
CD86
树突状细胞
淋巴结
T细胞受体
泛素
生物
化学
抗原提呈细胞
T细胞
免疫系统
免疫学
细胞生物学
基因
遗传学
作者
Carlos A. Castellanos,Xin Ren,Steven Lomeli Gonzalez,Hong Kun Li,Andrew Schroeder,Hong-Erh Liang,Brian J. Laidlaw,Donglei Hu,Angel C. Y. Mak,Celeste Eng,José Rodríguez‐Santana,Michael A. LeNoir,Qi Yan,Juan C. Celedón,Esteban G. Burchard,Scott S. Zamvil,Satoshi Ishido,Richard M. Locksley,Jason G. Cyster,Xiaozhu Huang,Jeoung‐Sook Shin
出处
期刊：Science immunology
[American Association for the Advancement of Science]
日期：2021-10-16
卷期号：6 (64)
被引量：14
标识
DOI：10.1126/sciimmunol.abh0707
摘要
Type 2 immune development depends on MARCH1-mediated turnover of MHCII and CD86 by lymph node–resident dendritic cells.
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