癌症研究
瓦博格效应
转移
生物
安普克
肿瘤进展
癌基因
上皮-间质转换
癌症
癌细胞
激酶
蛋白激酶A
细胞周期
细胞生物学
遗传学
作者
Li Shi,Yu Liu,Yifeng Bai,Min Chen,Donghui Cheng,Mengwan Wu,Jianling Xia
出处
期刊:Hepatology
[Lippincott Williams & Wilkins]
日期:2020-11-18
卷期号:73 (6): 2361-2379
被引量:41
摘要
RHOF helps tumor cells resist metabolic stress through modulating the Warburg effect and plays a critical role in promoting HCC cell migration, invasion, and EMT, highlighting its important role in remodeling the metastatic microenvironment and regulating tumor metastasis. RHOF shows potential as a therapeutic target and prognostic biomarker for HCC.
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