Assessment of Pack injection cells and the relationship between hematocrit of pack cells and the increase in hematocrit in patients with thalassemia

Background and aims: The amount of injected blood in patients with thalassemia is of particular importance and the blood amount is calculated based on the exact volume of Pack cell as well as their hematocrit. The aim of this study was to evaluate pack cells and the factors affecting on the amount of their hematocrit and their association with increase in hematocrit after blood injection. Methods: This is descriptive-analytical study. Characteristics including age, size, type of anticoagulant hemoglobin and hematocrit were recorded and one CBC was taken before injection and as well, one and twenty four hours after injection to assessment hemoglobin and hematocrit. The data were analyzed by SPSS. Results: The bag containing the anticoagulant substance CPDA-1 has more hematocrit than bags containing anticoagulant CPD + SAGM. Bags of low leukocytes have more hematocrit than bags of conventional type (P> 0.05). With increase in Pack cell volume, hematocrit will be decreased (P<0.001). Besides, the amount of hematocrit is more 24 hours after the injection than one hour later (P<0.001). Hct changes had a significant difference in the time before, also 1 and 24 hours after injection (P<0.001). Conclusion: Packet cell volume, type of anticoagulant and type of cell pack of the most important factors in the amount of hematocrit in blood bags that affects the hematocrit amount after injection.