Chemo‐selective Rh(II)/Pd(0) Dual Catalysis: Synthesis of All‐Carbon C3‐Quaternary Allylic Oxindoles from N‐Aryl‐α‐Diazo‐β‐Keto‐Amides with Functionalized Allyl Carbonates

Abstract A chemo‐selective Rh(II)/Pd(0) dual catalysis that promotes one‐pot synthesis of C3‐quaternary allylic oxindoles from N ‐aryl‐ α ‐diazo‐ β ‐ketoamides and functionalized allyl carbonates in good to excellent yields has been developed. The efficiency of this transformation relies on the choice of Rh(II)/Pd(0) dual catalysis strategy that enabled cascade intramolecular aryl C−H insertion and allylic alkylation under mild conditions. magnified image