医学
腹腔积液
乌司他丁
渗出
淀粉酶
生理盐水
治疗效果
脂肪酶
胃肠病学
药品
内科学
外科
药理学
酶
生物化学
化学
作者
Cong Feng,Hao Yang,Sai Huang,Xuan Zhou,Lili Wang,Xiang Cui,Li Chen,Faqin Lv,Tanshi Li
出处
期刊:Pancreatology
[Elsevier]
日期:2019-03-01
卷期号:19 (2): 285-289
被引量:4
标识
DOI:10.1016/j.pan.2019.01.013
摘要
To study the therapeutic effect of early local drug therapy on pancreatic contusion and laceration. Twenty pigs were divided into 4 groups: model(PL), 1 ml of saline; medical protein glue (EC), 1 ml of medical protein glue; ulinastatin (UL), 50000U of ulinastatin; combined treatment (UE), 1 ml of medical protein glue and 50000U of ulinastatin. 30 min after model establishment, different groups received different local drug treatments. The pancreatic function, peritoneal effusion and pancreatic pathology were observed. The UE group got the best therapeutic effect. The changes of pancreatic function and the peritoneal effusion were compared with PL group as follows. 0-6h: amylase (p < 0.01), lipase (p > 0.05), effusion (p < 0.01); 6-12h: amylase (p > 0.05), lipase (p < 0.01), effusion (p < 0.01); 12-24h: amylase (p < 0.01), lipase (p < 0.01), effusion (p < 0.01). Early local drug therapy in pancreatic contusion and laceration could effectively control the development of the disease and improve the prognosis.
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