丝状体
转移
下调和上调
线粒体ROS
线粒体
生物
癌症研究
癌细胞
细胞生物学
细胞迁移
癌症
乳腺癌
细胞
肌动蛋白
基因
生物化学
遗传学
作者
Venugopalan Cheriyath,Jaspreet Kaur,Anne Davenport,Ashjan F. Khalel,Nobel Chowdhury,Lalitha Gaddipati
标识
DOI:10.1038/s41416-018-0137-3
摘要
G1P3-induced mtROS have a direct role in migratory structure formation and nuclear gene expression to promote breast cancer cell metastasis. Therefore, interrupting mitochondrial functions of G1P3 may improve clinical outcomes in breast cancer patients.
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