Protein Posttranslational Modification: A Potential Target in Pharmaceutical Development

This chapter contains sections titled: Introduction What Is Protein Posttranslational Modification? Overview of Protein Posttranslational Modification Why Proteins Need to be Modified? Prokaryotic versus Eukaryotic PTM Studies of PTM Mapping of PTM Sites on RIP140 by LC–ESI–MS/MS Analysis The role of PTM in Cellular Function and Signaling Protein Posttranslational Modification and Diseases PTM as a Target for Therapeutic Development Conclusion Acknowledgment References