T细胞受体
转录组
T细胞
表型
计算生物学
生物
细胞
杠杆(统计)
癌症研究
生物信息学
作者
Pierre L. Levy,Alena Gros
出处
期刊:Cancer Cell
[Elsevier]
日期:2022-05-01
卷期号:40 (5): 447-449
标识
DOI:10.1016/j.ccell.2022.04.013
摘要
In this issue of Cancer Cell, Hanada et al. leverage single-cell multi-omics of lung cancer resident lymphocytes to identify phenotypic and transcriptomic signatures differentially expressed by neoantigen-reactive clonotypes. These findings could substantially expedite the selection of neoantigen-specific T cell receptors (TCRs) for individualized T cell therapies.
科研通智能强力驱动
Strongly Powered by AbleSci AI