Background: As a global chronic disease, diabetes is associated with high morbidity and cannot be fully cured with current technology.In order to achieve better long-term control of glucose, it requires continuous monitoring of metabolic indices.The most commonly used glucose monitor is finger stick testing glucose meters.When using it as a method for frequent glucose monitoring, it can cause physical discomfort, infection risk and contradiction.Noninvasive glucose monitoring can accomplish painless, risk-free, low-cost and frequent testing of glucose, which is an ideal method for self-monitoring of glucose.Aims: To verify the accuracy of noninvasive blood glucose monitor based on metabolic heat conformation method in patients with type 2 diabetes.The Noninvasive Glucose Monitor: Based on the theory of metabolic heat conformation method, Tsinghua University and Beijing Sunicare Medical Technologies Co., Ltd.developed a noninvasive glucose monitor.The monitor includes a host and a probe, as shown in Fig. 1.The probe is like a finger clip and the sensors are located inside the probe.The host is like an ipad, which is used for human-computer interaction, control the signal acquisition, data processing and result presenting.