海藻糖酶
生物
海藻糖
运输机
糖
糖原
碳水化合物代谢
生物化学
中肠
新陈代谢
葡萄糖转运蛋白
RNA干扰
碳水化合物
细胞生物学
功能(生物学)
线粒体
昆虫
酶
核糖核酸
代谢途径
基因沉默
繁殖
作者
Yongkang Liu,Yanlin Luo,Liwen Guan,Sijing Wan,Xian-Zhong Wang,Caidi Xu,Binghua Xie,Shigui Wang,Bin Tang
摘要
Abstract Sugar transporters play a crucial role in insect life activities, especially in energy metabolism and carbohydrate management. Sugar transporter 1 (St1) is a facilitative glucose transporter highly expressed in the midgut of Nilaparvata lugens (Stål) (Hemiptera: Delphacidae), however its physiological function remains unclear. To explore its pest control potential, we used RNA interference (RNAi) to investigate St1’s effects on sugar metabolism and female reproduction. Silencing St1 lowered membrane-bound trehalase (TRE2) activity and inhibited the hydrolysis of trehalose into glucose, impeding glycogen accumulation and glucose availability. Our findings show St1 regulates female reproduction by modulating trehalase activity. This study reveals St1’s crucial role in insect physiology and highlights it as a potential target for new, eco-friendly insecticides.
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