[Clinical value of capsule endoscopy in small intestinal diseases].

Objective: To analyze the clinical value of capsule endoscopy (CE) in small intestinal diseases and to explore the correlation between the diagnosis and clinical characteristics. Methods: From June 2016 to April 2019, a total of 194 patients receiving CE were enrolled in the Department of Gastroenterology, Shanxi People's Hospital, including 68 patients with obscure gastrointestinal bleeding, 104 with chronic abdominal pain and 22 with diarrhea. Results: The detection rate of small intestinal lesions by CE was 53.6%(104/194), of which gastrointestinal bleeding was 66.2% (45/68), chronic abdominal pain was 53.8%(56/104), and diarrhea was 13.6%(3/22). The first three positive diagnostic criteria of CE for gastrointestinal bleeding were non-specific inflammation, small intestinal ulcer and vascular malformation. CE findings in patients with abdominal pain were non-specific inflammation, small intestinal ulcer and Crohn's disease; while the major endoscopic presentations in patients with diarrhea were small intestinal ulcer and non-specific inflammation. Logistic regression analysis suggested that the clinical manifestations and gender were correlated with positive diagnosis by CE (P<0.05), and the positive diagnostic rate of CE in female patients was significantly lower than that in male patients [31.6%(25/79) vs. 51.3%(59/115), P<0.05]. The diagnostic rates of CE in patients with gastrointestinal bleeding and chronic abdominal pain were similar [55.9%(38/68) vs. 41.4%(43/104)], which was significantly higher than those with diarrhea [9.1%(2/22), P<0.05]. Conclusions: Capsule endoscopy has a high detection rate for small intestinal diseases, which could be the first choice in patients with unexplained gastrointestinal bleeding. Male patients and gastrointestinal bleeding are predictors of positive findings by CE.目的： 分析胶囊内镜（CE）在小肠疾病诊断中的临床价值，探讨受检者临床特征对CE阳性诊断结果的预测价值。 方法： 回顾性分析2016年6月至2019年4月在山西省人民医院消化科因不明原因消化道出血、慢性腹痛、腹泻行CE检查的患者资料。共194例患者纳入研究，其中消化道出血68例，慢性腹痛104例，腹泻22例。 结果： CE的小肠病变检出率为53.6%（104/194），其中消化道出血患者的小肠病变检出率为66.2%（45/68），慢性腹痛患者为53.8%（56/104），腹泻患者为13.6%（3/22）。CE检出的主要病变，在消化道出血患者为非特异炎症、小肠溃疡和血管畸形，在腹痛患者为非特异炎症、小肠溃疡及克罗恩病，在腹泻患者为小肠溃疡、非特异炎症。女性的CE阳性诊断率明显低于男性[31.6%（25/79）比51.3%（59/115），P<0.05]；消化道出血患者与慢性腹痛患者相比，CE阳性诊断的构成比的差异无统计学意义[55.9%（38/68）比41.4%（43/104），P>0.05]，均明显高于腹泻患者[9.1%（2/22），P<0.05]。对CE的小肠疾病阳性诊断结果与受检者临床特征关系进行logistic回归分析，结果显示，患者的性别、临床表现与CE阳性诊断结果有关联（P<0.05），男性、消化道出血史可作为CE阳性诊断的预测因素。 结论： （1）CE对小肠疾病的检出率较高，对于不明原因消化道出血患者可作为首选检查方法。（2）男性、消化道出血史可作为CE阳性诊断的预测指标。.