对映体
色氨酸
环糊精
化学
荧光
氨基酸
组合化学
立体化学
有机化学
生物化学
物理
量子力学
作者
Weijia Jiang,Ran He,Li Han,Xinheng He,Li Wang,Yanli Wei
出处
期刊:ACS Sensors
[American Chemical Society]
日期:2023-11-02
卷期号:8 (11): 4264-4271
被引量:1
标识
DOI:10.1021/acssensors.3c01616
摘要
Chiral recognition of amino acid plays a significant role in pharmaceutical, medical, and food science. This study describes a chiral sensing system of β-cyclodextrin (β-CD)-coated sulfur quantum dots (CD-SQDs) for the selective fluorescence recognition of tryptophan (Trp) enantiomers. CD-SQDs were prepared by a facile assembly fission method and could selectively recognize L-Trp by the different binding ability between L/D-Trp and β-CD. The inclusion of L-Trp and the stereoselective catalysis of CD-SQDs enzyme mimics cause the increased fluorescence intensity of CD-SQDs, which has a linear response ranging from 10 to 500 nM and the detection limit as 2.3 nM. CD-SQDs also show great selectivity for L-Trp from the commercial compound amino acid injection. The study could provide an effective method for the chiral recognition of amino acid enantiomers based on the catalytic activity of nanoenzymes.
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