Shape Selectivity by Guest‐Driven Restructuring of a Porous Material

Abstract A flexible metal‐organic framework selectively sorbs para ‐ (pX) over meta ‐xylene (mX) by synergic restructuring around pX coupled with generation of unused void space upon mX loading. The nature of the structural change suggests more generally that flexible structures which are initially mismatched in terms of fit and capacity to the preferred guest are strong candidates for effective molecular separations.