The history and status quo of using fungicides and anti-microorganisms to control Botrytis cinerea at home and abroad were summarized. Then the mechanisms of action,biological activities and chemical structures of several types of main fungicides and anti-microorganisms,such as benzimidazoles,dicarboximides,pyrimidinamines,carbamates,strobilurin,phenylpyrroles,phenyl amines and cycloheximides,were introduced. The prevention suggestions of Botrytis cinerea resistance to fungicide were proposed.