Efficient Reducing System Based on Iron for Conversion of Nitroarenes to Anilines

Abstract Reduction of nitroarenes with low solubility in EtOH–H2O to anilines easily occurs in a Fe–NH4Cl–acetone–H2O system, and treatment of the same nitroarenes with Fe–NH4Cl–EtOH–H2O hardly furnished the corresponding products. Under the reaction condition, the reducible or hydrolysable groups are not affected. Keywords: AnilineFe–NH4Cl–acetone–H2Onitroarenereduction ACKNOWLEDGMENT The work was financed by Grant No. JSDXKYZZ0801 from Jishou University for talent introduction, Hunan Province, China, and by a project (JSU-CX-2009-42) of College Students' Research-Type Learning and Innovative Experiment from Jishou University, Hunan, China.