Application of multiwalled carbon nanotubes/ionic liquid modified electrode for amperometric determination of sulfadiazine

A highly sensitive amperometric sulfadiazine sensor based on coating multiwalled carbon nanotubes (MWCNTs) and N‐octyl‐pyridinium‐hexafluorophosphate (OPPF 6 ) ionic liquid composite on a glassy carbon (GC) electrode is described. The MWCNTs/OPPF 6 composite contributed new properties to electrochemical sensors by combining the advantages of both ionic liquids and MWCNTs. Compared with bare GC electrode, the electrocatalytic activity of MWCNTs/OPPF 6 generated a greatly improved electrochemical detection of sulfadiazine including low oxidation potential, high current responses, and good anti‐fouling performance. The oxidation peak currents of sulfadiazine obtained on the MWCNTs/OPPF 6 coated GC electrode were proportional to the concentration of sulfadiazine within the range of 3.3‐35.4 μM with a detection limit of 0.21 μM. Copyright © 2011 John Wiley & Sons, Ltd.