羟甲基
抗菌活性
立体化学
枯草芽孢杆菌
苯并呋喃
呋喃
化学
金黄色葡萄球菌
乙酸乙酯
皮兰
传统医学
有机化学
生物
细菌
医学
遗传学
作者
Bin Wu,Wen Hui Lin,Hui Gao,Lu Zheng,Wu Li,Chul Sa Kim
标识
DOI:10.1080/13880200600798502
摘要
Four novel chemical constituents, cannabiside B, cannabiside C, cannabiloid B, and cannabilactone A, have been isolated from the n.-butanol extract of the herb of Senecio cannabifolius. Less. (Compositae). The structures of the isolated compounds were established as 3-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxyfuran-2(5H)-one (1), 8,10-dihydroxy-7-(hydroxymethyl)-4-methyl-1, 6-dioxaspiro [4.5] dec-3-en-2-one (2), 6-(1,2-dihydroxy-ethyl)-3-[3-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-hydroxy-pyrrol-2-ylidene]-4-hydroxy-tetrahydro-pyran-2-one (3), and 5-hydroxy-3-{[5-(hydroxylmethyl)furan-2-yl] methylene} benzofuran-2(3H)-one (4), respectively, by spectroscopic (UV, IR, NMR, and MS) methods. All the compounds showed antibacterial activities against Staphylococcus aureus. and Bacillus subtilis. but not Escherichia coli..
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