医学
心房颤动
内科学
心脏病学
瓣膜性心脏病
重症监护医学
风险因素
糖尿病
疾病
心力衰竭
肥胖
内分泌学
作者
Melissa E. Middeldorp,Jonathan Ariyaratnam,Dennis H. Lau,Prashanthan Sanders
出处
期刊:Heart
[BMJ]
日期:2019-11-11
卷期号:106 (5): 325-332
被引量:95
标识
DOI:10.1136/heartjnl-2019-315327
摘要
The management of atrial fibrillation (AF) has focused on anticoagulation, rhythm control and ventricular rate control. Recently, a fourth pillar of AF management has been incorporated recognising the importance of risk factor management (RFM). There are several risk factors that contribute to the development and progression of AF, these include traditional risk factors such as age, hypertension, heart failure, diabetes and valvular heart disease. However, increasingly it is recognised that obesity, sleep apnoea, hyperlipidaemia, smoking, alcohol, physical inactivity, genetics, aortic stiffness are associated with the development of AF. Importantly, several of these risk factors are modifiable. We have seen the evolution of RFM programmes which have demonstrated promising results. Indeed, the evidence is now so compelling that major clinical guidelines strongly advocate that aggressive treatment of these risk factors as a key component of AF management. Patients with AF who comprehensively managed their risk factors demonstrate greater reduction in symptoms, AF burden, more successful ablations and improved outcomes with greater AF freedom. In this article, we will review the evidence for the association between cardiac risk factors and AF and assess the burgeoning evidence for improved AF outcomes associated with aggressive cardiac RFM.
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