废止
化学
范围(计算机科学)
基质(水族馆)
组合化学
反应条件
金属
催化作用
有机化学
计算机科学
海洋学
程序设计语言
地质学
作者
Lianhong Jiao,Yanan Wang,Lixia Ding,Chaofeng Zhang,Xiao-Na Wang,Junbiao Chang
标识
DOI:10.1021/acs.joc.2c02103
摘要
A novel metal-free annulation of ynamides with 2H-azirines catalyzed by BF3·Et2O is described, leading to the construction of polysubstituted 2-aminopyrroles in a facile, flexible, and atom-economical way. This synthetic strategy proceeds with efficiency, broad substrate scope, and short reaction time under mild reaction conditions. Furthermore, the obtained annulation products could be modified to generate diverse 2-iminopyrrole frameworks in high yields.
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