巴比妥酸
突触
精神分裂症（面向对象编程）
神经科学
化学
心理学
精神科
生物化学
NMDA受体
受体
作者
Funda Orhan,Susmita Malwade,Neda Khanlarkhani,Asimenia Gkogka,Angelika Langeder,Oscar Jungholm,Marja Koskuvi,Šárka Lehtonen,Lilly Schwieler,Kent Jardemark,Jari Tiihonen,Jari Koıstınaho,Sophie Erhardt,Göran Engberg,Samudyata Samudyata,Carl M. Sellgren
标识
DOI：10.1176/appi.ajp.20240048
摘要
Together, these results link genetic risk variants for schizophrenia to elevated production of KYNA and excessive and activity-dependent internalization of synaptic material in microglia, while implicating pharmacological inhibition of KATs as a strategy to avoid synapse loss in schizophrenia.
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(2025-6-4)
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