鼠李糖乳杆菌
肽
化学
氨基酸
氢键
范德瓦尔斯力
猝灭(荧光)
疏水效应
酰胺
乳酸菌
有机化学
生物化学
荧光
分子
物理
量子力学
发酵
作者
Yuezhen Ouyang,Shiying Nie,Xinquan Yang,Xin Xu,Miao Zhou,William Kwame Amakye,Erdong Yuan,Jiaoyan Ren
标识
DOI:10.1021/acs.jafc.3c07318
摘要
Growing concern is about the potential side effects of nanomaterials from food packaging, notably zinc oxide nanoparticles (nZnO). Previous research revealed that walnut-derived peptides could mitigate this inhibitory effect, but the mechanism involved is unclear. Here, we found that not all peptides have such an effect. Based on the growth inhibition model of Lactobacillus rhamnosus LRa05 induced by nZnO, we assessed the protective effects of various peptides. Notably, four peptides containing charged amino acids (PPKNW, WPPKN, ADIYTE, and WEREEQE) were found to effectively alleviate the growth inhibition phenomenon. We hypothesize that the peptide–nZnO interaction modifies this effect, as confirmed through infrared, Raman, and fluorescence spectroscopy. Our results highlight amide bonds, amino groups, carboxyl groups, and benzene rings as key peptide binding sites on nZnO, with static quenching primarily due to hydrogen bonds and van der Waals forces. This study elucidates peptide characteristics in nZnO interactions, facilitating a deeper exploration of food matrix–nanocomposite interactions.
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