微流控
聚二甲基硅氧烷
材料科学
纳米技术
表面张力
润湿
接触角
数字微流体
超疏水涂料
电润湿
表面微加工
微尺度化学
微通道
毛细管作用
光电子学
物理
制作
复合材料
病理
电介质
替代医学
医学
量子力学
作者
Siyuan Xing,Ryan S. Harake,Tingrui Pan
出处
期刊:Lab on a Chip
[The Royal Society of Chemistry]
日期:2011-10-11
卷期号:11 (21): 3642-3642
被引量:99
摘要
Droplet-based transport phenomena driven by surface tension have been explored as an automated pumping source for a number of chemical and biological applications. In this paper, we present a comprehensive theoretical and experimental investigation of unconventional droplet-based motions on a superhydrophobic-patterned surface microfluidic (S(2)M) platform. The S(2)M surfaces are monolithically fabricated using a facile two-step laser micromachining technique on regular polydimethylsiloxane (PDMS) chemistry. Unlike the traditional droplet-driven pumps built on an enclosed microfluidic network, the S(2)M network pins the liquid-solid interface of droplets to the lithographically defined wetting boundary and establishes a direct linkage between the volumetric and hydraulic measures. Moreover, diverse modes of droplet motions are theoretically determined and experimentally characterized in a bi-droplet configuration, among which several unconventional droplet-driven transport phenomena are first demonstrated. These include big-to-small droplet merging, droplet balancing, as well as bidirectional transporting, in addition to the classic small-to-big droplet transition. Furthermore, multi-stage programmable bidirectional pumping has been implemented on the S(2)M platform, according to the newly established droplet manipulation principle, to illustrate its potential use for automated biomicrofluidic and point-of-care diagnostic applications.
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