丁基羟基苯甲醚
色谱法
没食子酸丙酯
萃取(化学)
化学
丁基羟基甲苯
溶剂
浊点
高效液相色谱法
对苯二酚
化妆品
检出限
有机化学
抗氧化剂
作者
Chang Liu,Jin Wang,Yongjian Yang
出处
期刊:Analytical Methods
[The Royal Society of Chemistry]
日期:2014-06-30
卷期号:6 (15): 6038-6038
被引量:21
摘要
A new and efficient cloud-point extraction (CPE) method for the determination of antioxidants including propyl gallate (PG), tertiary butyl hydroquinone (TBHQ), butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT) in cosmetics has been established combining with high-performance liquid chromatography (HPLC). The non-ionic surfactant dodecylpolyoxyethylene ether (AEO9) was chosen as an extraction solvent due to its low cloud-point temperature and short phase separation time and it is well-known as an environmentally friendly solvent. Factors affecting CPE (volume of the extraction solvent, sample pH, extraction time, and equilibration temperature) were optimized. Under the optimised conditions, detection limits in the range from 1.4 to 8.5 ng mL−1 were obtained. Linearity is over a wide range from 1 to 1000 μg mL−1 with a relative standard deviation under 4.8%. The high recoveries of the spiked cosmetics were obtained in the range of 90–110%. It was successfully utilized to determine the amounts of antioxidants in real cosmetics without the need for tedious pretreatments.
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