State of Anxiety and Depression of Acute Leukemia Patients Treated with Chemotherapy and Its Relation with Quality of Life

Objective To study the state of anxiety and depression of acute leukemia patients treated with chemotherapy and explore its relation with quality of life.Methods The questionnaire surrey was conducted among acute leukemia patients treated with chemotherapy by using Hospital Anxiety and Depression Scale(HAD) and European Organization for Research and Treatment of Cancer(EORTC QLQ-C30).Results The incidence rate of anxiety of acute leukemia patients treated with chemotherapy was 38.6%,the incidence rate of depression was 27.7%.Anxiety level was positively related to depression(r=0.857,P0.001).Compared between anxiety and non-anxiety groups there was a statistical difference in quality of life as the whole(P0.001);and there were statistical differences in such factional scales as emotional function,cognition function,social function,general health condition,fatigue,nausea,vomiting,pain,insomnia,anorexia,economic problem,somatic function,dyspnea,constipation,and diarrhea(P0.05).However no statistical significance was found in role function(P0.05).Conclusion Psychological problems of acute leukemia patients treated with chemotherapy are severe,their incidence rates of anxiety and depression are high.The general level of quality of life of the patients with anxiety is lower,which is evident in the majority of their life indications.