Study of Stability Influence Factors of Eugenol and Cinnamaldehyde with Different Existence State

Objective To investigate the stability of eugenol and cinnamaldehyde in powder,volatile oil,fat-soluble ointment,beta-CD inclusion compound and mixture. Methods Stability factors test was conducted for each sample,the content of eugenol and cinnamaldehyde was determined by high performance liquid chromatography(HPLC),and the retention rate was calculated. Results After light irradiation at 6000 lx for 10 days,eugenol had the retention rate of 77.79 %, 95.19 %, 63.12 %, 69.27 %, 0.00 %, and cinnamaldehyde had the retention rate of 91.67 %,89.26 %,63.38 %,66.36 %,0.00 % at different presence states. After heated at temperature of 60 ℃ for 10 days,eugenol had the retention rate of 83.16 %,93.98 %,77.14 %,80.30 %,23.01 %,and cinnamaldehyde had the retention rate of 4.36 %, 90.49 %, 64.00 %, 84.17 %, 24.92 % in different presence states. Conclusion The instability of eugenol and cinnamaldehyde varies in different presence states,and the sduty will provide reference for the development of their preparation and storage.