The methanolic extract of the leaves of Buchanania Lanzan was investigated for its anti inflammatory activity in animal models. The extract at different doses used showed good anti inflammatory activity which has been done significantly, by the formation of oedema induced by carrageenan. These results were also comparable to aspirin, the reference drugs used in this study. The results from present study indicate the efficacy of the methanolic extract as a therapeutic agent in acute as well as chronic inflammatory conditions. Thus it could be concluded that Buchanania Lanzan leaves extracts possess significant anti-inflammatory properties.