Selective solid-phase extraction of phenylcarbamic acid derivatives from a rat serum by molecularly imprinted polymer

Molecularly imprinted polymer (MIP) was synthesized using a non-covalent imprinting approach. Methacrylic acid was used as the functional monomer, acetonitrile was used as the porogen and 1-methyl-2-piperidinoethylester of 4-decyloxyphenylcarbamic acid as the imprint molecule (template). Imprinted polymer was utilized as the sorbents for solid-phase extraction (MISPE) to extract derivatives of alkoxyphenylcarbamic acid from spiked rat serum.