Theoretical and experimental investigation of the polyeletrophilic β-enamino diketone: straightforward and highly regioselective synthesis of 1,4,5-trisubstituted pyrazoles and pyrazolo[3,4-d]pyridazinones
作者
Michael J. V. da Silva,Raí G. M. Silva,Ulisses Zonta de Melo,Davana S. Gonçalves,Davi F. Back,Sidnei Moura,Rodrigo M. Pontes,Ernani A. Basso,Gisele F. Gauze,Fernanda A. Rosa
出处
期刊:RSC Advances [Royal Society of Chemistry] 日期:2015-12-22卷期号:6 (1): 290-302被引量:19
标识
DOI:10.1039/c5ra12968k
摘要
A highly efficient regioselective synthesis of 1,4,5-trisubstituted pyrazoles and pyrazolo[3,4- d ]pyridazinones from enamino diketone along with a theoretical and experimental study of the chemical reactivity enamino diketone.