Lactobacillus rhamnosus Is Protective Against Experimental Necrotizing Enterocolitis in the Setting of Cronobacter sakazakii Infection

immunocompromised mice and assigned the following interventions after the tumor was >300 mm on ultrasound measurement: intra-tumoral implantation of sponges containing (1) vincristine 25 mg (Vin25S); (2) 50mg (Vin50S); (3) doxorubicin 200 mg (Dox200S); (4) 400 mg (Dox400S); or (5) drug-free sponge (CONT), with 8 mice per group. An equivalent dosage of the most effective drug was administered intravenously after sham surgery. Tumor growth was analyzed using ANOVA and logistic regression. Tumor sections were stained with hematoxylin and eosin, TUNEL assay, and Ki67.