生物利用度
微乳液
药物输送
纳米囊
药品
化学
胶束
固体脂质纳米粒
纳米载体
纳米技术
生化工程
纳米颗粒
药理学
医学
材料科学
工程类
水溶液
有机化学
肺表面活性物质
生物化学
作者
Li Jiau Huang,Xuehua Huang,Xi Yang,James W. Hu,Yizhun Zhu,Pingkun Yan,Yan Li
标识
DOI:10.1016/j.phrs.2024.107100
摘要
The development of natural products for potential new drugs faces obstacles such as unknown mechanisms, poor solubility, and limited bioavailability, which limit the broadened applicability of natural products. Therefore, there is a need for advanced pharmaceutical formulations of active compounds or natural products. In recent years, novel nano-drug delivery systems (NDDS) for natural products, including nanosuspensions, nanoliposomes, micelle, microemulsions/self-microemulsions, nanocapsules, and solid lipid nanoparticles, have been developed to improve solubility, bioavailability, and tissue distribution as well as for prolonged retention and enhanced permeation. Here, we updated the NDDS delivery systems used for natural products with the potential enhancement in therapeutic efficiency observed with nano-delivery systems.
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