To emulate the tactile perception of human skin, the integration of tactile sensors with neuromorphic devices has emerged as a promising approach to achieve near-sensor information processing. Here, we present a monolithic electronic device that seamlessly integrates tactile perception and neuromorphic computing functionalities within a single architecture, with synaptic plasticity directly tunable by tactile inputs. This unique capability stems from our engineered device structure employing SnO 2 nanowires as the conductive channel coupled with a pressure-sensitive chitosan layer ionic gating layer. The device demonstrates pressure-dependent memory retention and learning behaviors, effectively mimicking the enhanced cognitive functions observed in humans under stressful conditions. Furthermore, the integrated design exhibits potential for implementing bioinspired electronic systems requiring adaptive tactile information processing.