First-in-Human PET Imaging of MT1-MMP in a Patient with Breast and Muscle-Invasive Urothelial Bladder Cancer Using the Bicyclic Radiotracer [68Ga]Ga-BCY25286

Membrane type 1 matrix metalloproteinase (MT1-MMP) is overexpressed in various solid tumors, contributing to tumor invasion, metastasis, and poor prognosis ([1][1]). To date, a clinical translation has not yet been accomplished ([2][2]). Here, we report the first-in-human clinical translation of MT1